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The Other Diabetes
May 14th, 2012
Like other mainstream media, the Wall Street Journal rarely notices type 1 diabetes (or, as I have suggested, “autoimmune diabetes”). But in a recent article on prevention of autoimmune diabetes, the Journal floated a new name for “our” diabetes: it is now the other diabetes. The distinction between type 1 and type 2 diabetes goes back [...]
Glucose Meters Conquer the World
April 30th, 2012
The personal glucose meter is the most important advance in diabetes care in my thirty-five years of living with type 1. What if this humble machine is the killer app that will reform health care? Personal electronic devices are transforming commerce through disintermediation, meaning that the internet and high-speed computing give you direct access to [...]
What to Eat for DiaBeat
April 16th, 2012
The algorithms that fill my computer and iPhone screens long ago figured out that I have diabetes, or at least I am very interested in it. Aside from diabetes books and blood sugar supplies, it seems the next level of ads are promoting foods that help diabetics. Some ads imply that a new herb from [...]
Designing a Definitive Islet Sheet Study
April 2nd, 2012
Large-animal studies will demonstrate whether the Islet Sheet is ready for a clinical trial. In previous posts I have discussed the partnership doing this study: the Cedars-Sinai Diabetes and Obesity Research Institute, the islet transplantation group at UC Irvine, and our company Islet Sheet Medical. I have also laid out the study design. Today I want to describe [...]
Looking for a Ton of Islets
March 19th, 2012
The Islet Sheet is an encapsulation technology designed to work with any cell that secretes anything of therapeutic value. Hanuman Medical Foundation is funding the Islet Sheet Project with the goal of demonstrating that we can cure people with type 1 diabetes with sheets containing primary islets — that is, islets of Langerhans isolated from [...]
My Favorite Pages
March 5th, 2012
Over the past six months, Hanuman Medical Foundation has consolidated three websites to create this one devoted to explaining and reporting on the Islet Sheet Project. Our company, Islet Sheet Medical, provided many of the graphics used to explain islet transplantation and the Islet Sheet. (The company no longer has its own website.) So now [...]
“Glucose Responsive Insulin” Will Not Improve the Lives of Type 1 Diabetics
February 19th, 2012
I spend time studying developments in diabetes research, and when possible I like to help other diabetes decision makers with my analysis. Today I am sharing a letter I sent to the president of Juvenile Diabetes Research Fund (JDRF), Jeffrey Brewer, explaining why I think their Glucose Responsive Insulin program is highly unlikely to produce [...]
Design Protocol for Large-Animal Islet Sheet Study
January 30th, 2012
My last posting marked the start of trials at the new Cedars-Sinai lab to determine the efficacy of the Islet Sheet in large mammals—a long-awaited goal. It also talked about Professor Richard Bergman’s vision for his new Diabetes and Obesity Research Institute there. The fact that Bergman, known as a leader in type 2 research, [...]
The Crucial Year for Islet Sheet is 2012
January 17th, 2012
A year ago I posted an article to this blog titled “The Crucial Year for Islet Sheet is 2011.” I was off by a year, as it turned out; last year was a transition year. The crucial year begins today. As I wrote last year, “The definitive experimental model is large animals (pig, dog, monkey) [...]
Advice for Paul of Michigan
January 2nd, 2012
Question: Hi Scott – my name is Paul B***** from Oxford, Michigan. I am a type 1 diabetic, diagnosed at age six. I am now studying Cell and Molecular Biology as an undergrad at Grand Valley State University. I was reading your work, and I’ve become fascinated with the idea of bioengineering and immunology. It’s [...]
