Islet Sheet Medical Useful Methods

High Guluronate Alginate

Edited by Randy Dorian, Vice-President

July 1, 1997

This alginate may elicit some foreign body response. The alginate forms a strong gel when contacted with calcium. It is useful for an initial coating, as described in U.S. patent number 5,643,594 by Randel E. Dorian, Kent C. Cochrum and Richard David Antanavich, assigned to the Regents of the University of California. The calcium gel is stable indefinitely in vivo. Click here to see the entire patent at the IBM patent web site. We recommend that you use the ISM revised method.