RANDY DORIAN

randy@cercomedical.com
Hanuman Medical
PlasmaSeal L.L.C.
Cerco Medical, L.L.C.
2180 Palou Ave.
San Francisco, CA 94124

(415) 902-1201
















Positions and Employment

2001-pres     Director, Sperm Analytics LLC
1999-pres     Director, Truffles International LLC
1998-pres.    Executive V.P., Hanuman Medical  LLC
1996-pres.    Chief Science Officer, Cerco Medical LLC
1993-pres.    Senior V.P., PlasmaSeal LLC
1991-1993   Senior Scientist and Director of Process Development, Transtech Medical, Inc.
1990-1991     Research Director, Trigenesis
1987-1992.      V.P., Research and Development and Director, California Truffle Co, Inc.
1985-1987      Director of Research and Development, BabaGene, Inc.
1981-1985      Senior Scientist in charge of Cell Isolation Technology, BioResponse, Inc.
1983-1985      Scientific Consultant, University of California at San Francisco
1982-1983      Scientific Consultant, University of California at San Diego
1979-1981      Research Associate, University of California at San Diego
1977-1979      Research Associate, Salk Institute for Biological Studies
1975-1976      Consultant in Mathematics, Rand Corporation
1973-1977      Research Technician, University of California at San Diego
1971-1972      Student Research Fellow, Scripps Institute of Oceanography
1970-1971      Army Scholar, Salk Institute for Biological Studies

Education and Honors

B.S., Biochemistry, 1975, Revelle College, University of California at San Diego
Honorary Doctorate in Aerospace Medicology (AMD), 1971, USAF Systems Command, Aerospace Medical Division

Publications

  • Dorian R., Bernheim, J. and Mendelsohn, J. Quantification of Entry into and Exit From the Cell Cycle in Phytohemagglutinin Stimulated Human Lymphocyte Cultures. Cell Tis. Kinet. 1973, 11, 33.
  • Bernheim, J., Dorian, R. and Mendelsohn, J. DNA Synthesis and Cell Proliferation in Stimulated Human Lymphocyte Cultures: Kinetics of Response to Phytohemagglutinin. J. Exptl. Med. 1973, 120 955.
  • Bernheim J., Dorian R., Djobadza M. and Mendelsohn, J. Lymphocyte PHA and PPA Stimulation as an In Vitro model for Recruitment: Proliferation Kinetics of the System. Cancer Treatment Reports, 1976, 1986.
  • Bernheim J., Dorian, R., Kelley, M. and Mendelsohn, J. Kinetics of DNA Synthesis, Cell Proliferation and Cell Death in Human Lymphocyte Stimulation by Phytohemagglutinin (PHA). Fed. Proc. 1976, 35, 821.
  • Bernheim J., Dorian, R. and Mendelsohn, J. "Pitfalls in the Lymphocyte Proliferation Assay: Variations in Proliferation Kinetics and Cold Thymidine Pools." Proc. 11th Leukocyte Culture Conf., Academic Press, 1977, 464.
  • Mendelsohn, J., Dorian, R., Castagnola, J. and Bernheim, J. "Is There Gene Amplification or Other Non-Duplicative DNA Synthesis in Phytohemagglutinin Stimulated Human Lymphocyte Cultures?" Proc. 11th Leukocyte Conf. Academic Press, 1977, 467.
  • Dorian, R., Mendelsohn, J. and Bernheim, J. Quantification of Entry Into and Exit From the Cell Cycle; An Analytical Method Without Pharmacological Perturbation. Scand. J. Immunol. 1977, 464.
  • Bernheim, J., Mendelsohn, J., Kelley, J. and Dorian, R. Kinetics of Death and Disintegration in Human Lymphocyte Cultures. Proc. Natl. Acad. Sci. 1977, 74, 2356.
  • Bernheim J., Dorian, R. and Mendelsohn, J. Kinetics of Lymphocyte Response to PHA and PPD Effects on Cell Density and Balance of DNA Synthesis and Mitosis. Scand. J. Immunol. 1977, 6, 681.
  • Fahey, R., Newton, G., Dorian R. and Kosower E. Analysis of Biological Thiols: Derivatization with Monobromotrimethylammoniobimane and Characterization by Electrophoresis and Chromatography. Anal. Biochem. 1980, 107, 1.
  • Fahey, R., Newton, G. Dorian, R. and Kosower, E. Analysis of Biological Thiols: Quantitative Determination of Thiols at the Picomole Level Based Upon Derivatization with Monobromobimane and Separation by Cation-Exchange Chromatography. Anal. Biochem. 1981, 111, 357.
  • Newton, G., Dorian, R. and Fahey, R. Analysis of Biological Thiols: Derivatization with Monobromobimanes and Separation by Reverse Phase High Performance Liquid Chromatography. Anal. Biochem. 1981, 114, 393.
  • Fahey, R., Dorian R. and Utley, I. New Methods for Analysis of WR2721, WR1065 and WR33278. Intl. J. Onc. Bio. Phys. 1981.
  • Cochrum, K., Jemtrud, S., and Dorian, R., Successful Xenografts in Mice with Microencapsulated Rat and Dog Islets. Transplant Proc, 1995 27, 3297-3301.
  • Storrs, R.W., Dorian, R., King, S., Lakey, J., and Rilo, H.. Preclinical Development of the Islet Sheet, Annals of the New York Academy of Sciences Vol. 944, October 2001.
  • King, S., Dorian, R. Storrs, R.W.,  Lakey, J. Requirements for Encapsulation Technology and the Challenges for Transplantation of Islets of Langerhans, Graft Vol. 4(7), pp. 491-9, Oct/Nov 2001.

Patents

  1. Retrievable bioartificial implants having dimensions allowing rapid diffusion of oxygen and rapid biological response to physiological change, processes for their manufacture, and methods for their use  (6,372,244)
  2. Plasma concentrate and method of processing blood for same  (6,214,338)
  3. Retrievable bioartificial implants having dimensions allowing rapid diffusion of oxygen and rapid biological response to physiological change, processes for their manufacture, and methods for their use (6,165,225)
  4. Apparatus for applying tissue sealant (6,132,396)
  5. Method and apparatus for making concentrated plasma and/or tissue sealant (6,063,297)
  6. Retrievable bioartificial implants having dimensions allowing rapid diffusion of oxygen and rapid biological response to physiological change (5,855,613)
  7. Method and apparatus for applying tissue sealant (5,814,022)
  8. Methods for making concentrated plasma and/or tissue sealant  (5,788,662)
  9. Non-fibrogenic high mannuronate alginate coated transplants, processes for their manufacture, and methods for their use (5,693,514)
  10. Spin encapsulation apparatus and method of use (5,643,594)
  11. Electrostatic process for manufacturing coated transplants and product (5,639,467)
  12. Plasma concentrate and tissue sealant methods and apparatuses for making concentrated plasma and/or tissue sealant (5,585,007)
  13. Multiple layer alginate coatings of biological tissue for transplantation (5,578,314)
  14. Microcapsule generating system containing an air knife and method of encapsulating (5,521,079)
  15. Cells or tissue coated with non-fibrogenic alginate less than 200 m thick   (5,656,468)
  16. Sperm motility assay and devices (5,434,057)
  • Non-fibrogenic high mannuronate alginate coated transplants, processes for their manufacture, and methods for their use (5,429,821)

Patent applications and provisional patents

  1. U.S. Application No. 20030205538
  2. U.S. Application No. 10/176,272
  3. U.S. Provisional Application No. 60/377,559
  4. U.S. Provisional Application No. 60/379,951
  5. U.S. Provisional Application No. 60/382,639
  6. U.S. Application No. 10/394,801
  7. U.S. Application No. 10/394,828
  8. U.S. Provisional Application No. 60/397,001
  9. PCT Application No. PCT/US03/2217
  10. PCT Application No. PCT/US03/12288